Brain is the most important organ in living being’s body and it is the most complex organ to understand. To capture the brain we have to know about what are the things inside brain and what kind of methodology can be used for capture. Below article will give you guys a little understanding about capturing neurons inside brain.
What is Neural Network?
Neural network is interconnected nerve cells called neurons which especially in nervous system in brain.
What is Calcium Channel Imaging?
Calcium channel imaging, basically want to do is taking photographs of how neurons functioning and this is done using Ca+2 ions.
Methodology of Analyzing Neural Networks Using Calcium Channel Imaging
Calcium ions (Ca+2) generate versatile intracellular signals that control key functions in all types of neurons. Imaging calcium in neurons is particularly important because calcium signals exert their highly specific functions in well-defined cellular sub compartments. In this Primer, we briefly review the general mechanisms of neuronal calcium signaling. We then introduce the calcium imaging devices, including co focal and two-photon microscopy as well as miniaturized devices that are used in freely moving animals. We provide an overview of the classical chemical fluorescent calcium indicators and of the protein-based genetically encoded calcium indicators. Using application examples, we introduce new developments in the field, such as calcium imaging in awake, behaving animals and the use of calcium imaging for mapping single spine sensory inputs in cortical neurons in brain. We conclude by providing an outlook on the prospects of calcium imaging for the analysis of neuronal signaling and plasticity in various animal models.
Chemical Ingredients Used for Calcium Channel Imaging
- Fluorescent Ca2+ antagonists
- Dihydropyridines
- Phenylalklyamines
Above chemical ingredients are used for this calcium image channel.
There are lots of methodologies and lots of researches ongoing to capture how brain is functioning.
Maneesha Indrachapa 